Antioxidative 7-Oxodehydropodocarpane-Type Trinorditerpenes from the Bark of Taiwania cryptomerioides

Abstract

Five new 7-oxopodocarpane-type trinorditerpenes together with 1β,13,14-trihydroxy-8,11,13-podocarpatrien-7-one (1) were isolated from the bark of Taiwania cryptomerioides. By using NMR and other spectral methods, the structures of five new compounds, 14-hydroxy-13-methoxy-8,11,13-podocarpatriene-3,7-dione (2), 1β,14-dihydroxy-13-methoxy-8,11,13-podocarpatrien-7-one (3), 13,14-dihydroxy-8,11,13-podocarpatriene-3,7-dione (4), 3β,13,14-trihydroxy-8,11,13-podocarpatrien-7-one (5), and 1β,13,14-trihydroxy-8,11,13-podocarpatriene-2,7-dione (6), were elucidated. Compounds 1, 4, 5, and 6 exhibited strong antioxidative activity.

Key words

Taiwania cryptomerioids - Taxodiaceae - podocarpane - antioxidative activity

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