Planta Med 2002; 68(11): 1020-1023
DOI: 10.1055/s-2002-35648
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Antioxidative 7-Oxodehydropodocarpane-Type Trinorditerpenes from the Bark of Taiwania cryptomerioides

Yueh-Hsiung Kuo1 , Shih-Chang Chien1 , Ching-Chuan Kuo1
  • 1Department of Chemistry, National Taiwan University, Taipei, Taiwan, Republic of China
Further Information

Publication History

Received: November 16, 2001

Accepted: June 29, 2002

Publication Date:
26 November 2002 (online)

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Abstract

Five new 7-oxopodocarpane-type trinorditerpenes together with 1β,13,14-trihydroxy-8,11,13-podocarpatrien-7-one (1) were isolated from the bark of Taiwania cryptomerioides. By using NMR and other spectral methods, the structures of five new compounds, 14-hydroxy-13-methoxy-8,11,13-podocarpatriene-3,7-dione (2), 1β,14-dihydroxy-13-methoxy-8,11,13-podocarpatrien-7-one (3), 13,14-dihydroxy-8,11,13-podocarpatriene-3,7-dione (4), 3β,13,14-trihydroxy-8,11,13-podocarpatrien-7-one (5), and 1β,13,14-trihydroxy-8,11,13-podocarpatriene-2,7-dione (6), were elucidated. Compounds 1, 4, 5, and 6 exhibited strong antioxidative activity.

References

Prof. Yueh-Hsiung Kuo

Department of Chemistry, National Taiwan University

Taipei 106

Taiwan R.O.C.

Email: yhkuo@ccms.ntu.edu.tw

Phone: +886-223638146

Fax: +886-223636359